Lophophora williamsii

Also known as Peyote. It will never grow to more than about four inches (10 centimer) in diameter. Instead, new appear at the base of the old ones, forming characteristic peyote clusters. The number of ribs and their arrangement vary with age and environment; the number of ribs can range from four when very young to fourteen in maturity. Grow may take five years when grown from seeds to reach a 3/4 inch (2.5 centimer) diameter. Peter Stafford – Psychedelic Encyclopedia

One consituent in peyote — peyocactin, which is also called hordonine–has been shown by James McCleary and his colleagues at California State University, Fullterton, to be an antibiotic active against a wide spectrum of bacteria, having an inhibitory action against at least eighteen strains of penicillin-resistant Staphylococcusaureus. This antibacterial characteristic may account in part for its healing effects when applied to wounds. Another area that should be probed further is peyote’s effect upon eye-sight. The peyote literature included many reports of restoration of vision. – Peter Stafford – Psychedelic Encyclopedia


A light dose of peyote is 50-100g fresh or 10-20g dry, which equates in either case to roughly three to six mid-sized buttons. Moderate doses range up to 150g fresh or 30g dry (six to twelve buttons), while strong doses range up to 200g fresh or 40g dry (eight to sixteen buttons). Anything above this is considered heavy.


It is hard to be precise, however, due to the varying levels of mescaline in any given peyote button. Growing location and season of harvest can also affect their potency, as can ageā€”older peyote tends to be more potent.

In episode 3 Dr. Martin Terry mentions (with scientific data backing it) that if you harvest Peyote sustainably, it will take 8 years for it to grow back to the same size.

Peyote (Mescaline) tea preparation:

  1. cut the Peyote button in very thin slices
  2. put 2 litres of water in a pan, add powder and add 1 squeezed lemon or lime
  3. boil for 8 hours, add water when needed
  4. in the pan is now a fluid with a glue-like texture
  5. put this in a different container by filtering through a cheesecloth
  6. simmer this fluid on a low heat until it fits in a tea cup

Take this tea on an empty stomach to limit the amount of nausea.